PHARMACOLOGY FURTHER E-NEWSLETTER
JANUARY '25
Is Pharmacology Difficult®️
JANUARY FDA APPROVED DRUGS :
Datopotamab Deruxtecan-dlnk (Datroway) Lyophilised powder for injection was approved by FDA on January 17, 2025. It is a TROP 2 Directed Antibody and Topoisomerase inhibitor conjugate for the treatment of Hormone receptor positive, Human epidermal growth factor receptor 2 (HER2) Negative breast cancer.
Treosulfan (Grapafex) Lyophilised powder for injection was approved on January 21, 2025 for Stem Cell Transplant Conditioning. It is an alkylating agent to be used in combination with fludarabine in adults as well as paediatric patients of one year of age and older people with Acute Myeloid Luekemia (AML) or Myelodysplastic Syndrome (MDS).
Tocilizumab-anoh (Avtozma) Injection was approved on January 24, 2025. It is an Interleukin 6 receptor antagonist (IL 6), biosimilar to Actemra. It is used for the treatment of Rheumatoid Arthritis, Giant cell Arteritis, Polyarticular Juvenile Idiopathic Arthritis, Systemic Juvenile Idiopathic Arthritis.
Miloxicam & Rizatriptin (Symbravo) Tablets were approved on January 30, 2025. It is a Non Steroidal Antiinflammatory drug and triptan combination to be used for the treatment of Migraine with or without aura in adults.
Suzetrigine (Journavx) Tablets were approved on January 30, 2025. It is a sodium channel blocker to be used for the treatment of moderate to severe acute pain in adults.
LATEST MEDICAL UPDATES:
Latest research:
Latest study from a renowned Medical Journal-BMJ, states that using contemporary hormonal contraceptives on regular basis increases risk of Ischemic stroke.
Latest research from a renowned journal- Annals of Clinical & Translational Neurology states that women who suffer from Epilepsy generally bear offsprings with decreased bone metabolism.
One of the study done by Harvard University states that employees in United States suffer quite a lot with chronic health ailments and this adversely affects their work lives and productivity.
A recent study from JAMA Network open states that Young people inclined towards Nicotine & Tobacco use often suffer from related Attention Deficit Hyperactivity Disorder (ADHD).
Current research from American heart Association states that Infection Related Hospitalisation (IRH) is linked to heart failure with reduced ejection fraction.
FROM MY CLASSROOM:
Here I will be sharing some insights of Pharmacology learnings from the classes I have taken this month or all that I have read in the subject.
My own reading topic comprises of Influenza and its treatment:
Flu (Influenza) is a respiratory illness one gets from Influenza virus
Symptoms include fever, head and body aches, coughing and stuffy/runny nose.
One should be vaccinated every year to avoid complications
People with asthma, COPD, Lung diseases are at more risk
Influenza A,B,C are the most common types of viruses affecting people, e.g. H1N1 (Swine flu) and bird flu
It is contagious and spreads from direct or indirect contact
Nose swab test is the test for influenza
Antivirals help a lot to cure early and shorten sickness time
Antiviral medications include- Oseltamivir, Zanamivir, Peramivir, Baloxavir marboxil
Side effects include Nausea, diarrhoea and bronchospasm.
One should take plenty of rest, stay hydrated, NSAIDs to relieve fever, head and body ache.
Cough suppressants (antitussives) and expectorants can calm the cough.
Preventive measures include getting vaccinated yearly
One can wear mask, avoid sharing utensils
The problem can last from few days to two weeks.
Radgin Wiz®️
From Radgin Wiz Writing desk:
I recently visited Mahakumbh 2025 in Prayagraj , Uttar Pradesh.
I am deeply impressed and motivated to write a travelogue about my visit and experience.
Here are few tips to write an influential travelogue- do your research nicely
Write descriptively and highlight the various attractions
Give all the details of vehicles etc to reach the destination- their types, charges etc.
Also mention different types of hotels, stay rooms etc for say along with their charges.
Mention the common and rare places of tourist attractions
Explain the traditional heritage and cultural richness of the place
Give a detailed list of do’s and don’ts at the place and also the important points to be cautious about.
SIMPLE AND SPARKLING:
BAY LEAF- MORE THAN A SPICE!!
Bay leaf comes from the bay tree (Laurus nobilis). The tree os commonly found in Mediterranean region
Chemicals in bay leaf help people to control blood sugar and cholesterol levels- it is observed though not yet thoroughly proved.
Bay leaves are used much in pickling, marinating and stewing, etc. Essential oil component is mainly cineole.
It adds low calories to food , boosts the fiber, vitamins, minerals and antioxidants
Bay leaves contain good amount of vitamin A, Vitamin B6 and Vitamin C
They are also rich in iron and manganese
Can be added to vegetables, curries, as tea, added to soups.
They can ease bouts of upset stomach
Tea is quite aromatic, can relive sinus/runny nose.
Off the Cuff Talks:
ESSENCE OF SELF PAMPERING
Self Pampering are intentional acts of self care which makes one feel rejuvenated, relaxed and ready for ones goals after episodes of stress, hard work, etc
Some common acts are massage, spa, reading book, playing game, going out to eat, spending time with kids, going to cinema
These activities reduce stress, improve mood and self esteem.
Such acts of self kindness increase relaxation and improve quality of life.
Some good examples are listening to music, taking a facial, getting nails done, taking a walk in natural surroundings, shopping, cooking or baking
It is not a selfish act
One and everyone deserves it.
It is an investment in physical, mental and emotional well being
It relieves from pressures of daily life and lessens anxiety.
It is well said- “Take time to love yourself, you deserve it.”
Well, That’s all from my end in this Spectacularly curated combo of January ‘25 Issue. Hope it satisfies your quest for information and medical updates and News. Greet you all on the Next issue is (on its way)….
PLEASE SPREAD THE WORD AND SUBSCRIBE!!
IT IS A MOTIVATION TO MY EFFORTS…..:))